Two New Lavandulyl Flavonoids from Sophora flavescens
نویسندگان
چکیده
منابع مشابه
Tyrosinase inhibitory prenylated flavonoids from Sophora flavescens.
For the purpose of the development of a skin-whitening agent, Sophora flavescens was evaluated for tyrosinase inhibitory activity and its active principles were identified following activity-guided isolation. The ethanol extract and dichloromethane fraction from S. flavescens showed significant inhibition of mushroom tyrosinase. From the dichloromethane fraction, three known prenylated flavonoi...
متن کاملLavandulyl Flavonoids from Sophora flavescens Suppress Lipopolysaccharide-Induced Activation of Nuclear Factor-kB and Mitogen-Activated Protein Kinases
ance between oxidants and antioxidants at the cellular level, has shown a deep interest constantly as the cause of cardiovascular events and a variety of vascular diseases. One of the crucial steps in oxidative stress augmentation is the overproduction of reactive oxygen species (ROS). ROS encompass a variety of diverse chemical species including hydroxyl radical, nitric oxide (NO), and superox...
متن کاملHuman ACAT Inhibitory Effects of Flavonoids from Sophora flavescens
Acyl-coenzyme A:cholesterol acyltransferase (ACAT, EC 2.3.1.26) is the primary cellular enzyme that catalyzes the formation of cholesteryl esters from cholesterol and fatty acyl-coenzyme A. It has been identified that two isoenzymes, ACAT-1 and ACAT-2, have different cell locations, membrane orientations, and metabolic functions. Atherosclerotic lesions are associated with the accumulation of c...
متن کاملSelective Extraction of Flavonoids from Sophora flavescens Ait. by Mechanochemistry.
Flavonoids from Sophora flavescens were selectively extracted by mechanochemical-promoted extraction technology (MPET) after using response surface methodology to determine the optimal extraction parameters. The highest yield of 35.17 mg/g was achieved by grinding the roots with Na₂CO₃ (15%) at 440 rpm/min for 17.0 min and water was used as the sole solvent with a ratio of solvent to solid mate...
متن کاملLocalization of Prenylated Flavonoids in Sophora flavescens var. angustifolia Plants
A histochemical analysis was carried out on the distribution of flavonoid derivatives in Sophora flavescens var. angustifolia plant. Prenylated flavonoids such as kushenol I, kurarinone, sophoraflavanone G and des-O-methylanhydroicaritin were mainly localized in the peri derm (cork layers, and cork layer-like tissues scattered in parenchymatous tissues of the root system). Pterocarpan derivati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2010
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1000501210